Publications - Dynamique de la polarité épithéliale

NB: les articles de l'équipe sont pré-publiés sur BioRxiv depuis 2017

* Corresponding author(s)


The clathrin adaptor AP-1B independently controls proliferation and differentiation in the mammalian intestine
Duclos M, Bourdais A, Nicolle O, Michaux G*, Bidaud-Meynard A*
2023, BioRxiv

# MRCK controls myosin II activation in the polarized cortex of mouse oocytes and promotes spindle rotation and male pronucleus centration
Bourdais A, Dehapiot B, Halet G.
2023, J Cell Biol

Crb3 is required to organize the apical domain of multiciliated cells
C, Raitière J, Michaux G, Kodjabachian L, Le Bivic A
2023, J Cell Sci

SIN-3 transcriptional coregulator maintains mitochondrial hormesis and polyamine flux
Palladino F, Giovannetti M, Fabrizio P, Nicolle O, Bedet C, Rodriguez-Palero M, Michaux G, Artal-Sanz M and Witting M
2023, BioRxiv; in revision

Sparse denoising and adaptive estimation enhances the resolution and contrast of fluorescence emission difference microscopy based on array detector
Prigent S, Dutertre S, Bidaud-Meynard A, Bertolin G, Michaux G, Kervrann C.
2023, Optics Letter


V0-ATPase downregulation induces MVID-like brush border defects independently of apical trafficking in the mammalian intestine
Bidaud-Meynard A*, Nicolle O, Bourdais A, Duclos M, Saleh J, Ruemmele F, Farin HF, Delacour D, Moshous D, Michaux G*
2022, BioRxiv; in revision

PAR-4/LKB1 regulates intestinal cell number by restricting endoderm specification to the E lineage
Demouchy F, Nicolle O, Michaux G*, Pacquelet A*
2022, BioRxiv; in revision

UNC45A deficiency causes microvillus inclusion disease-like by impairing myosin VB–dependent apical trafficking
Rémi Duclaux-Loras, Corinne Lebreton, Jérémy Berthelet, Fabienne Charbit-Henrion, Ophélie Nicolle, Céline Revenu, Stephanie Waich, Taras Valovka, Anis Khiat, Marion Rabant, Caroline Racine, Chiara Guerrera, Júlia Baptista, Maxime Mahe, Michael Hess, Béatrice Durel, Nathalie Lefort, Céline Banal, Mélanie Parisot, Cécile Talbotec, Florence Lacaille, Emmanuelle Ecochard-Dugelay, Arzu Demir, Georg Vogel, Laurence Faivre, Astor Rodrigues, Darren Fowler, Andreas Janecke, Thomas Müller, Lukas Huber, Fernando Rodrigues-Lima, Frank Ruemmele, Holm Uhlig, Filippo Del Bene, Grégoire Michaux, Nadine Cerf-Bensussan, Marianna Parlato
2022, J Clin Invest


High resolution dynamic mapping of the C. elegans intestinal brush border
Bidaud-Meynard A, Demouchy F, Nicolle O, Pacquelet A, Suman SK, Plancke C, Robin F, Michaux G
2021, Development

# RhoA- and Cdc42-induced antagonistic forces underlie symmetry breaking and spindle rotation in mouse oocytes
Dehapiot B, Clément R, Bourdais A, Carrière V, Huet G, Halet G
2021, PLoS Biology

# Cofilin regulates actin network homeostasis and the length of microvilli in oocytes
Bourdais A, Dehapiot B, Halet G
2021, J Cell Sci

Super-resolved live-cell imaging using Random Illumination Microscopy
Thomas Mangeat, Simon Labouesse, Marc Allain, Awoke Negash, Emmanuel Martin, Aude Guénolé, Renaud Poincloux, Claire Estibal, Anaïs Bouissou, Sylvain Cantaloube, Elodie Vega, Tong Li, Christian Rouvière, Sophie Allard, Debora Keller, Valentin Debarnot, Xia Bo Wang,  Grégoire Michaux, Mathieu Pinot, Roland Le Borgne, Sylvie Tournier, Magali Suzanne, Jérôme Idier, Anne Sentenac
2021, Cell Reports Methods

Myosin-1b interacts with UNC45A and controls intestinal epithelial morphogenesis
Céline Revenu, Marianna Parlato, Marion Rosello, Karine Duroure, Rémi Duclaux-Loras, Ophélie Nicolle, Marie-Thérèse Prospéri, Julie Stoufflet, Juliette Vougny, Corinne Lebreton, Priscilla Lépine, Grégoire Michaux, Nadine Cerf-Benssusan, Evelyne Coudrier, Filippo Del Bene
2021, BioRxiv; in revision


C-terminal phosphorylation modulates ERM-1 localization and dynamics to control cortical actin organization and support lumen formation during C. elegans development
Ramalho JJ, Sepers JJ, Nicolle O, Schmidt R, Cravo J, Michaux G, Boxem M
2020, Development


Simultaneous regulation of cytokinetic furrow and nucleus positions by cortical tension contributes to proper DNA segregation during late mitosis
Pacquelet A*, Jousseaume M, Etienne J, Michaux G
2019, Current Biology

Force Transmission between Three Tissues Controls Bipolar Planar Polarity Establishment and Morphogenesis
Gillard G, Nicolle O, Brugière T, Prigent S, Pinot M, Michaux G
2019, Current Biology
Voir les actualités du CNRS et de l'Université de Rennes 1

V0-ATPase-dependent apical trafficking maintains the polarity of the intestinal absorptive membrane
Bidaud-Meynard A, Nicolle O, Heck M, Le Cunff Y, Michaux G
2019, Development


Dynamic formation of microvillus inclusions during enterocyte differentiation in Munc18-2 deficient intestinal organoids
Mosa MH, Nicolle O, Maschaldi S, Sepulveda FE, Bidaud-Meynard A, Menche C, Michels B, Michaux G*, de Saint Basile G*, Farin HF*
2018, Cellular and Molecular Gastroenterology and Hepatology


# Ces projets ont été initiés dans d'autres équipes avant que certains auteurs nous rejoignent en 2022.  


2017 and before

Contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity
Salomon J, Gaston C, Magescas J, Duvauchelle B, Canioni D, Sengmanivong L, Mayeux A, Michaux G, Campeotto F, Lemale J, Viala J, Poirier F, Minc N, Schmitz J, Brousse N, Ladoux B, Goulet O, Delacour D
2017, Nature Communications

The localisation of the apical Par/Cdc42 polarity module is specifically affected in microvillus inclusion disease
Michaux G*, Massey-Harroche D, Nicolle O, Rabant M, Brousse N, Goulet O, Le Bivic A*, Ruemmele FM*
2016, Biology of the Cell

PAR-4 and anillin regulate myosin to coordinate spindle and furrow position during asymmetric division
Pacquelet A*, Uhart P, Tassan JP, Michaux G
2015, Journal of Cell Biology
>> Journal of Cell Biology "biosight" video
>> CNRS highlight (in french)

Control of E-cadherin apical localisation and morphogenesis by a SOAP-1/AP-1/clathrin pathway in C. elegans epidermal cells
Gillard G, Shafaq-Zadah M, Nicolle O, Damaj R, Pécréaux J, Michaux G
2015, Development

Adaptation of cryo-sectioning for immuno-EM-labeling of asymmetric samples: C. elegans case study
Nicolle O, Burel A, Griffiths G, Michaux G, Kolotuev I.
2015, Traffic

GPSy: a cross-species gene prioritization system for conserved biological processes-application in male gamete development
Britto R, Sallou O, Collin O, Michaux G, Primig M, Chalmel F
2012, Nucleic Acids Res.

AP-1 is required for the maintenance of apico-basal polarity in the C. elegans intestine
Shafaq-Zadah M, Brocard L, Solari F, Michaux G
2012, Development

A role for Rab10 in Von Willebrand Factor release discovered by an AP-1 interactor screen in C. elegans
Michaux G*, Dyer CEF, Nightingale TD, Gallaud E, Nurrish S, Cutler DF*
2011, J Thromb Haemost.

Anticancer drug 5-fluorouracil induces reproductive and developmental defects in Caenorhabditis elegans
Kumar S, Aninat C, Michaux G, Morel F
2010, Reprod Toxicol.

[Sorting, recycling and WNT signaling: Wntless and retromer functions]
Michaux G, Le Borgne R
Med Sci. 2009.

High-pressure freezing provides insights into Weibel-Palade body biogenesis
Zenner HL, Collinson LM, Michaux G, Cutler DF
J Cell Sci. 2007

Genes required for osmoregulation and apical secretion in Caenorhabditis elegans
Liégeois S, Benedetto A, Michaux G, Belliard G, Labouesse M
Genetics. 2007

P-selectin and CD63 use different mechanisms for delivery to Weibel-Palade bodies
Harrison-Lavoie KJ, Michaux G, Hewlett L, Kaur J, Hannah MJ, Lui-Roberts WW, Norman KE, Cutler DF
Traffic. 2006

The physiological function of von Willebrand's factor depends on its tubular storage in endothelial Weibel-Palade bodies
Michaux G, Abbitt KB, Collinson LM, Haberichter SL, Norman KE, Cutler DF
Dev Cell. 2006 Feb.

P-selectin binds to the D'-D3 domains of von Willebrand factor in Weibel-Palade bodies
Michaux G, Pullen TJ, Haberichter SL, Cutler DF
Blood. 2006 May.

An AP-1/clathrin coat plays a novel and essential role in forming the Weibel-Palade bodies of endothelial cells
Lui-Roberts WW, Collinson LM, Hewlett LJ, Michaux G, Cutler DF
J Cell Biol. 2005

CLN6, which is associated with a lysosomal storage disease, is an endoplasmic reticulum protein
Mole SE, Michaux G, Codlin S, Wheeler RB, Sharp JD, Cutler DF
Exp Cell Res. 2004

How to roll an endothelial cigar: the biogenesis of Weibel-Palade bodies
Michaux G, Cutler DF
Traffic. 2004

Analysis of intracellular storage and regulated secretion of 3 von Willebrand disease-causing variants of von Willebrand factor
Michaux G, Hewlett LJ, Messenger SL, Goodeve AC, Peake IR, Daly ME, Cutler DF
Blood. 2003

Epithelial biology: lessons from Caenorhabditis elegans
Michaux G, Legouis R, Labouesse M
Gene. 2001

The Caenorhabditis elegans gene lin-26 can trigger epithelial differentiation without conferring tissue specificity
Quintin S, Michaux G, McMahon L, Gansmuller A, Labouesse M
Dev Biol. 2001

CHE-14, a protein with a sterol-sensing domain, is required for apical sorting in C. elegans ectodermal epithelial cells
Michaux G, Gansmuller A, Hindelang C, Labouesse M
Curr Biol. 2000

Sequence and analysis of a 26.9 kb fragment from chromosome XV of the yeast Saccharomyces cerevisiae
Boyer J, Michaux G, Fairhead C, Gaillon L, Dujon B
Yeast. 1996