Publications de l'équipe SP@RTE


Spatio-temporal dynamics of the DNA glycosylase OGG1 in finding and processing 8-oxoguanine.
Cintori L, Di Guilmi AM, Canitrot Y, Huet S, Campalans A.
DNA Repair, Jul 2023.

Annihilation-free chemical theory of subatomic particles.
Avner S*, Richard P.
Qeios, Jul 2023.

The histone methyltransferase NSD3 contributes to sister chromatid cohesion and to cohesin loading at mitotic exit.
Eot-Houllier G*, Magnaghi-Jaulin L, Bourgine G, Smagulova F, Giet R, Watrin E, Jaulin C*.
J Cell Sci, Jun 2023.

Modular antibodies reveal DNA damage-induced mono-ADP-ribosylation as a second wave of PARP1 signaling.
Longarini EJ, Dauben H, Locatelli C, Wondisford AR, Smith R, Muench C, Kolvenbach A, Lynskey ML, Pope A, Bonfiglio JJ, Pinto Jurado E, Fajka-Boja R, Colby T, Schuller M, Ahel I, Timinszky G, O'Sullivan RJ, Huet S*, Matic I*.
Mol Cell, May 2023.

HPF1-dependent histone ADP-ribosylation triggers chromatin relaxation to promote the recruitment of repair factors at sites of DNA damage.
Smith R#*, Zentout S#, Rother M, Bigot N, Chapuis C, Mihuț A, Zobel FF, Ahel I, van Attikum H, Timinszky G*, Huet S*.
Nat Struct Mol Biol, Apr 2023.

Identification of key residues of the DNA glycosylase OGG1 controlling efficient DNA sampling and recruitment to oxidized bases in living cells.
D'Augustin O, Gaudon V
, Siberchicot C, Smith R, Chapuis C, Depagne J, Veaute X, Busso D, Di Guilmi AM, Castaing B, Radicella JP, Campalans A*, Huet S*.
Nucleic Acid Res, Apr 2023.

Codon adaptation by synonymous mutations impacts the functional properties of the estrogen receptor-alpha protein in breast cancer cells.
Clusan L, Percevault F, Jullion E, Le Goff P, Tiffoche C, Fernandez-Calero T, Métivier R, Marin M, Pakdel F, Michel D, Flouriot G.
Mol Oncol, Feb 2023.

OGG1 competitive inhibitors show important off-target effects by directly inhibiting efflux pumps and disturbing mitotic progression.
Tanushi X, Pinna G, Vandamme M, Siberchicot C, d'Augustin O, Di Guilmi AM, Radicella JP, Castaing B, Smith R, Huet S, Leteurtre F, Campalans A.
Front Cell Dev Biol, Feb 2023.

One model fits all: combining inference and simulation of gene regulatory networks.
Ventre E, Herbach U, Espinasse T, Benoit G, Gandrillon O.

PLOS Comput. Biol., Feb 2023.

The different natural estrogens promote endothelial healing through distinct cell targets.
Davezac M, Zahreddine R, Buscato M, Smirnova NF, Febrissy C, Laurell H, Gilardi-Bresson S, Adlanmerini M, Liere P, Flouriot G, Guennoun R, Laffargue M, Foidart JM, Lenfant F, Arnal JF, Métivier R, Fontaine C.
JCI Insight, Feb 2023.


Hypoxia and ERα Transcriptional Crosstalk Is Associated with Endocrine Resistance in Breast Cancer.
Jehanno C, Le Goff P, Habauzit D, Le Page Y, Lecomte S, Lecluze E, Percevault F, Avner S, Métivier R, Michel D*,  Flouriot G*
Cancers, Oct 2022.

Non-canonical miRNA-RNA base-pairing impedes tumor suppressor activity of miR-16.
Quéméner AM, Bachelot L, Aubry M, Avner S, Leclerc D, Salbert G, Cabillic F, Decaudin D, Mari B, Mouriaux F, Galibert MD, Gilot D.
Life Sci. Alliance, Oct 2022.

5-methylcytosine turnover: Mechanisms and therapeutic implications in cancer.
Turpin M, Salbert G.
Front Mol Biosci., Aug. 2022.

PCSK9 deficiency results in a specific shedding of excess LDLR in female mice only: Role of hepatic cholesterol.
Roubtsova A, Garçon D, Lacoste S, Chamberland A, Marcinkiewicz J,
Métivier R, Sotin T, Paquette M, Bernard S, Cariou B, Le May C, Koschinsky ML, Seidah NG, Prat A.
Biochim Biophys Acta Mol Cell Biol Lipids., Aug. 2022.

TGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity.
Fougerat A, Schoiswohl G, Polizzi A, Régnier M, Wagner C, Smati S, Fougeray T, Lippi Y, Lasserre F, Raho I, Melin V, Tramunt B, Métivier R, Sommer C, Benhamed F, Alkhoury C, Greulich F, Jouffe C, Emile A, Schupp M, Gourdy P, Dubot P, Levade T, Meynard D, Ellero-Simatos S, Gamet-Payrastre L, Panasyuk G, Uhlenhaut H, Amri EZ, Cruciani-Guglielmacci C, Postic C, Wahli W, Loiseau N, Montagner A, Langin D, Lass A, Guillou H.
Cell Rep., Jun 2022.

Usage of the H3 variants during the S-phase of the cell cycle in Physarum polycephalum.
Thiriet C.
Nucleic Acid Res. Mar 2022.

TET2-mediated epigenetic reprogramming of breast cancer cells impairs lysosome biogenesis.
Laurent A, Madigou T, Bizot M, Turpin M, Palierne G, Mahé E, Guimard S, Métivier R, Avner S, Le Péron C*, Salbert G*.
Life Sci. Alliance, Mar 2022.

The N-terminal domain of TET1 promotes the formation of dense chromatin regions refractory to transcription.
Lejart A, Zentout S, Chapuis C, D'Augustin O, Smith R, Salbert G*, Huet S*.
Chromosoma, Mar 2022.

The conundrum of the functional relationship between transcription factors and chromatin.
Salbert G, Sérandour AA, Staels B, Lefebvre P, Eeckhoute J.
Epigenomics, Mar 2022.

A general mathematical model for the in vitro assembly dynamics of intermediate filament proteins.
Mücke N, Wocjan T,
Jacquier M, Herrmann H, Portet S.
Biophys. J, Feb 2022.


Zinc finger protein ZNF384 is an adaptor of Ku to DNA during classical non-homologous end-joining.
Kaur Singh J,
Smith R, Rother MB, de Groot AJL, Wiegant WW, Vreeken K, D'Augustin O, Kim RQ, Qian H, Krawczyk PM, González-Prieto R, Vertegaal ACO, Lamers M, Huet S, van Attikum H.
Nat Commun, Nov 2021.

Conceiving particles as undulating granular systems allows fundamentally realist interpretation of quantum mechanics.
Avner S.
Entropy, Oct 2021.

New Methodologies to Study DNA Repair Processes in Space and Time Within Living Cells.
Zentout S, Smith R, Jacquier M, Huet S.
Front. Cell Dev. Biol., Sept 2021.

RhoA- and Cdc42-induced antagonistic forces underlie symmetry breaking and spindle rotation in mouse oocytes.
Dehapiot  B, Clément  R, Bourdais  A, Carrière V,
Huet S, Halet G.
Plos biol 2021 Sep.

ETV6-RUNX1 and RUNX1 directly regulate RAG1 expression: one more step in the understanding of childhood B-cell acute lymphoblastic leukemia leukemogenesis.
Jakobczyk H#, Jiang Y#, Debaize L, Soubise B,
Avner S, Sérandour AA, Rouger-Gaudichon J, Rio AG, Carroll JS, Raslova H, Gilot D, Liu Z, Demengeot J, Salbert G, Douet-Guilbert N, Corcos L, Galibert MD, Gandemer V, Troadec MB
Leukemia 2021 Sept. 

Label-free microscopy of mitotic chromosomes using the polarization orthogonality breaking technique.
Desapogu R, Le Marchand G, Smith R, Ray P, Gillier E, Dutertre S, Alouini M, Tramier M, Huet S*, Fade J*.
Biomed Opt Express 2021 Jul. 

Serine-linked PARP1 auto-modification controls PARP inhibitor response.
Prokhorova E, Zobel F,
Smith R, Zentout S, Gibbs-Seymour I, Schützenhofer K, Peters A, Groslambert J, Zorzini V, Agnew T, Brognard J, Nielsen ML, Ahel D, Huet S, Suskiewicz MJ, Ahel I.
Nat Commun 2021 Jul.

Nuclear translocation of MRTFA in MCF7 breast cancer cells shifts ERα nuclear/genomic to extra-nuclear/non genomic actions.
Jehanno C, Percevault F, Boujrad N, Le Goff P, Fontaine C, Arnal JF, Primig M, Pakdel F, Michel D, Métivier R, Flouriot G.
Mol Cell Endocrinol. 2021 Apr.

Autophagy facilitates mitochondrial rebuilding after acute heat stress via a DRP-1-dependent process.
Chen Y, Leboutet R, Largeau C,
Zentout S, Lefebvre C, Delahodde A, Culetto E, Legouis R.
J Cell Biol 2021 Apr.

Reduction of RUNX1 transcription factor activity by a CBFA2T3-mimicking peptide: application to B cell precursor acute lymphoblastic leukemia.
Jakobczyk H#, Debaize L#, Soubise B, Avner S, Rouger-Gaudichon J, Commet S, Jiang Y, Sérandour AA, Rio AG, Carroll JS, Wichmann C, Lie-A-Ling M, Lacaud G, Corcos L, Salbert G, Galibert MD, Gandemer V, Troadec MB.
J Hematol Oncol. 2021 Mar.

Estetrol prevents Western diet-induced obesity and atheroma independently of hepatic estrogen receptor α.
Buscato M, Davezac M, Zahreddine R, Adlanmerini M, Métivier R, Fillet M, Cobraiville G, Moro C, Foidart JM, Lenfant F, Gourdy P, Arnal JF, Fontaine C.
Am J Physiol Endocrinol Metab. 2021 Jan


The chromatin remodeler ALC1 underlies resistance to PARP inhibitor treatment.
Juhász S#, Smith R#, Schauer T, Spekhardt D, Mamar H, Zentout S, Chapuis C, Huet S*, Timinszky G*
Science Advances 2020 Dec. 

CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks.
Rother MB, Pellegrino S, Smith R, Gatti M, Meisenberg C, Wiegant WW, Luijsterburg MS, Imhof R, Downs JA, Vertegaal ACO, Huet S, Altmeyer M, van Attikum H
Nat Commun 2020 Nov. 

Lost in the Crowd: How Does Human 8-Oxoguanine DNA Glycosylase 1 (OGG1) Find 8-Oxoguanine in the Genome?
D'Augustin O, Huet S*, Campalans A*, Radicella JP*.
Int J Mol Sci. 2020 Nov. 

Tamoxifen Accelerates Endothelial Healing by Targeting ERα in Smooth Muscle Cell.  
Zahreddine R, Davezac M, Smirnova NF, Buscato M, Lhuillier E, Lupieri A, Solinhac R, Vinel A, Vessieres E, Henrion D, Renault MA, Gadeau AP, Flouriot G, Lenfant F, Laffargue M, Metivier R, Arnal JF, Fontaine C.
Circ Res. 2020 Oct.

Electron mass predicted from substructure stability in electrodynamical model
Avner S*, Boillot F.
Front Phys. 2020 Jul.

Mutation of Arginine 264 on ERα (Estrogen Receptor Alpha) Selectively Abrogates the Rapid Signaling of Estradiol in the Endothelium Without Altering Fertility
Adlanmerini M, Chanaelle F, Zahreddine R, Vessières E, Buscato M, Solinhac R, Favre J, Anquetil T, Guihot AL, Boudou F, Raymond-Letron I, Chambon P, Gourdy P, Ohlsson C, Laurell H, Fontaine C, Metivier R, Le Romancer M, Henrion D, Arnal JF, Lenfant F.
Arterioscler Thromb Vasc Biol. 2020 Jul.

Nuclear accumulation of MKL1 in luminal breast cancer cells impairs genomic activity of ERα and is associated with endocrine resistance
Jehanno C, Fernandez-Calero T, Habauzit T, Avner S, Percevault F, Jullion E, Le Goff P,  May Coissieux M, Muenst S, Marin M, Michel D, Métivier R, Flouriot G.
BBA-Gene Regulatory Mechanisms 2020 Feb.


The RNA export factor Mex67 functions as a mobile nucleoporin. 
Derrer CP, Mancini R, Vallotton P, Huet S, Weis K, Dultz E.
J Cell Biol. 2019 Dec.

Poly(ADP-ribose)-dependent chromatin unfolding facilitates the association of DNA-binding proteins with DNA at sites of damage
Smith R, Lebeaupin T, Juhasz S, Chapuis C, D'Augustin O, Dutertre S, Burkovics P, Biertumpfel C, Timinszky G, Huet S.
Nucleic Acid Res. 2019 Sept.

The hydroxymethylome of multiple myeloma identifies FAM72D as a 1q21 marker linked to proliferation
Chatonnet F, Pignarre A, Sérandour AA, Caron G, Avner S, Robert N, Kassambara A, Laurent A, Bizot M, Agirre X, Prosper F, Martin-Subero JI, Moreaux J, Fest T*, Salbert G*.
Haematologica 2019 Jun.

Selective Liver Estrogen Receptor α Modulation Prevents Steatosis, Diabetes, and Obesity Through the Anorectic Growth Differentiation Factor 15 Hepatokine in Mice.
Guillaume M, Riant E, Fabre A, Raymond‐Letron I, Buscato M, Davezac M, Tramunt B, Montagner A, Smati S, Zahreddine R, Palierne G, Valera MC, Guillou H, Lenfant F, Unsicker K, Metivier R, Fontaine C, Arnal JF, Gourdy P.
Hepatology Comm. 2019 Apr.

Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy.
Pfitzer L, Moser C, Gegenfurtner F, Arner A, Foerster F, Atzberger C, Zisis T, Kubisch-Dohmen R, Busse J, Smith R, Timinszky G, Kalinina OV, Müller R, Wagner E, Vollmar AM, Zahler S.
Cell Death Dis. 2019 Apr.


Monitoring Poly(ADP-Ribosyl)ation in Response to DNA Damage in Live Cells Using Fluorescently Tagged Macrodomains.
Smith R, Timinsky G.
Methods Mol Biol. 2018.

Cytosine hydroxymethylation by TET enzymes: From the control of gene expression to the regulation of DNA repair mechanisms, and back.
Lejart A, Salbert G, Huet S.
AIMS BioPhys. 2018 Sep.

The multiple effects of molecular crowding in the cell nucleus: from molecular dynamics to the regulation of nuclear architecture.
Lebeaupin T, Smith R, Huet S.
in Nuclear Architecture and Dynamics, Translational Epigenetics Series. 2018.

acroH2A histone variants limit chromatin plasticity through two distinct mechanisms.
Kozlowski M, Corujo D, Hothorn M, Guberovic I, Mandemaker IK, Blessing C, Sporn J, Gutierrez‐Triana A, Smith R, Portmann T, Treier M, Scheffzek K, Huet S, Timinszky G, Buschbeck M, Ladurner AG.
EMBO Rep. 2018 Sep.

Interplay between transcription regulators RUNX1 and FUBP1 activates an enhancer of the oncogene c-KIT and amplifies cell proliferation.
Debaize L#, Jakobczyk H#, Avner S, Gaudichon J, Rio AG, Sérandour AA, Dorsheimer L, Chalmel F, Carroll JS, Zörnig M, Rieger MA, Delalande O, Salbert G, Galibert MD, Gandemer V, Troadec MB.
Nucleic Acids Res. 2018 Aug.

CHD3 and CHD4 recruitment and chromatin remodeling activity at DNA breaks is promoted by early poly(ADP-ribose)-dependent chromatin relaxation.
Smith R, Sellou H, Chapuis C, Huet S*, Timinszky G*.
Nucleic Acids Res. 2018 May.

Lymphatic Vasculature Requires Estrogen Receptor-α Signaling to Protect From Lymphedema.
Morfoisse F, Tatin F, Chaput B, Therville N, Vaysse C, Métivier R, Malloizel-Delaunay J, Pujol F, Godet AC, De Toni F, Boudou F, Grenier K, Dubuc D, Lacazette E, Prats AC, Guillermet-Guibert J, Lenfant F, Garmy-Susini B.
Arterioscler Thromb Vasc Biol. 2018 Apr.

Correlative live and super-resolution imaging reveals the dynamic structure of replication domains.
Xiang W, Roberti MJ, Hériché JK, Huet S, Alexander S, Ellenberg J.
J Cell Biol. 2018 Mar.

Coupling Exonuclease Digestion with Selective Chemical Labeling for Base-resolution Mapping of 5-Hydroxymethylcytosine in Genomic DNA.
Sérandour AA, Avner S, Salbert G.
Bio-protocol 2018 Mar.
Link to python script.

Reading cytosine modifications within chromatin.
Mahé EA, Madigou T, Salbert G.
Transcription 2018 Feb.


A Poly-ADP-Ribose Trigger Releases the Auto-Inhibition of a Chromatin Remodeling Oncogene.
Singh HR, Nardozza AP, Möller IR, Knobloch G, Kistemaker HAV, Hassler M, Harrer N, Blessing C, Eustermann S, Kotthoff C, Huet S, Mueller-Planitz F, Filippov DV, Timinszky G, Rand KD, Ladurner AG.
Mol Cell 2017 Dec.

The antagonist properties of Bazedoxifene after acute treatment are shifted to stimulatory action after chronic exposure in the liver but not in the uterus. 
Buscato M, Fontaine C, Fabre A, Vinel A, Valera MC, Noirrit E, Guillaume M, Payrastre B, Métivier R, Arnal JF.
Mol Cell Endocrinol. 2017 Nov.

Poly(ADP-Ribose)-Dependent Chromatin Remodeling in DNA Repair. 
Lebeaupin T, Smith R, Huet S, Timinszky G.
Methods Mol Biol. 2017 Jul.

Membrane and Nuclear Estrogen Receptor Alpha Actions: From Tissue Specificity to Medical Implications. 
Arnal JF, Lenfant F, Metivier R, Flouriot G, Henrion D, Adlanmerini M, Fontaine C, Gourdy P, Chambon P, Katzenellenbogen B, Katzenellenbogen J.
2017 May.

Cytosine modifications modulate the chromatin architecture of transcriptional enhancers
Mahé EA, Madigou T, Sérandour AA, Bizot M, Avner S, Chalmel F, Palierne G, Métivier R, Salbert G.
Genome Res. 2017 Apr.

5-hydroxymethylcytosine marks postmitotic neural cells in the adult and developing vertebrate central nervous system.
Diotel N, Mérot Y, Coumailleau P, Gueguen MM, Sérandour AA, Salbert G, Kah O.
J Comp Neurol. 2017 Feb.

Inactivation of the Nuclear Orphan Receptor COUP-TFII by Small Chemicals. 
Le Guével R, Oger F, Martinez-Jimenez CP, Bizot M, Gheeraert C, Firmin F, Ploton M, Kretova M, Palierne G, Staels B, Barath P, Talianidis I, Lefebvre P, Eeckhoute J, Salbert G.
ACS Chem. Biol. 2017 Jan.


A Point Mutation in a lincRNA Upstream of GDNF Is Associated to a Canine Insensitivity to Pain: A Spontaneous Model for Human Sensory Neuropathies.
Plassais J, Lagoutte L, Correard S, Paradis M, Guaguère E, Hédan B, Pommier A, Botherel N, Cadiergues MC, Pilorge P, Silversides D, Bizot M, Samuels M, Arnan C, Johnson R, Hitte C, Salbert G, Méreau A, Quignon P, Derrien T, André C.
PLOS Genetics 2016 Dec.

The AF-1-deficient estrogen receptor ERα46 isoform is frequently expressed in human breast tumors.
Chantalat E, Boudou F, Laurell H, Palierne G, Houtman R, Melchers D, Rochaix P, Filleron T, Stella A, Burlet-Schiltz O, Brouchet A, Flouriot G, Métivier R, Arnal JF, Fontaine C and Lenfant F.
Breast Cancer Res 2016 Dec.

The poly(ADP-ribose)-dependent chromatin remodeler Alc1 induces local chromatin relaxation upon DNA damage.
Sellou H, Lebeaupin T, Chapuis C, Smith R, Hegele A, Singh HR, Kozlowski M, Bultmann S, Ladurner AG, Timinszki G*, Huet S*.
Mol Biol Cell 2016 Oct.

Analysis of DNA Replication by Optical Mapping in Nanochannels.
Lacroix J, Pélofy S, Blatché C, Pillaire MJ, Huet S, Chapuis C, Hoffmann JS, Bancaud A.
Small, 2016 Sep.

A glucose-starvation response regulates the diffusion of macromolecules.
Joyner RP, Tang JH, Helenius J, Dultz E, Brune C, Holt LJ, Huet S, Müller DJ, Weis K.
eLife 2016 Mar.

Changes in gene expression and Estrogen Receptor cistrome in mouse liver upon acute E2 treatment.
Palierne G, Fabre A, Solinhac R, Le Péron C, Avner S, Lenfant F, Fontaine C, Salbert G, Flouriot G, Arnal JF, Métivier R.
Mol Endocrinol. 2016 May.

Single-CpG resolution mapping of 5-hydroxymethylcytosine by chemical labeling and exonuclease digestion identifies evolutionarily unconserved CpGs as TET targets.
Sérandour AA, Avner S, Mahé EA, Madigou T, Guibert S, Weber M, Salbert G
Genome Biol. 2016 Mar.



Cell cycle-dependent reconfiguration of the DNA (hydroxy)methylome during terminal differentiation of human B cells into plasma cells. 
Caron G, Hussein M, Kulis M, Delaloy C, Chatonnet F, Pignarre A, Avner S, Lemarié M, Mahé E, Verdaguer-Dot N, Queirós AC, Tarte K, Martín-Subero JI, Salbert G*, Fest T*. 
Cell Reports. 2015 Oct.

Chromatin dynamics at DNA breaks: what, how and why?
Lebeaupin T, Sellou H, Timinszky G, Huet S.
AIMS Biophysics, 2015.

Diffusion and partitioning of macromolecules in casein microgels: evidence for size-dependent attractive interactions in a dense protein system.
Peixoto PD, Bouchoux A, Huet S, Madec MN, Thomas D, Floury J, Gésan-Guiziou G.
Langmuir. 2015 Feb.

DNA demethylation by TET proteins: a potential therapeutic target in cancer.
Mahé E, Salbert G.
Epigenetic Diag Ther. Vol 1. 2015


Dynamic estrogen receptor interactomes control estrogen-responsive trefoil Factor (TFF) locus cell-specific activities.
Quintin J, Le Péron C, Palierne G, Bizot M, Cunha S, Sérandour AA, Avner S, Henry C, Percevault F, Belaud-Rotureau MA, Huet S, Watrin E, Eeckhoute J, Legagneux V, Salbert G, Métivier R
Mol Cell Biol. 2014 Jul.

Ensconsin/Map7 promotes microtubule growth and centrosome separation in Drosophila neural stem cells.
Gallaud E, Caous R, Pascal A, Bazile F, Gagné JP, Huet S, Poirier GG, Chrétien D, Richard-Parpaillon L, Giet R.
J Cell Biol. 2014 Mar.

Peroxisome proliferator-activated receptor γ regulates genes involved in insulin/insulin-like growth factor signaling and lipid metabolism during adipogenesis through functionally distinct enhancer classes.
Oger F, Dubois-Chevalier J, Gheeraert C, Avner S, Durand E, Froguel P, Salbert G, Staels B, Lefebvre P, Eeckhoute J.
J Biol Chem. 2014 Jan

Relevance and Limitations of Crowding, Fractal, and Polymer Models to Describe Nuclear Architecture. 
Huet S, Lavelle C, Ranchon H, Carrivain P, Victor JM, Bancaud A. 
In: "International Review of Cell and Molecular Biology Book Series". Vol 307, Chap 13, (éd. R. Hancock & K. Jeon), Elsevier Academic Press. 2014.


Crowded chromatin is not sufficient for heterochromatin formation and not required for its maintenance. 
Walter A, Chapuis C, Huet S*, Ellenberg J*.
J Struct. Biol. 2013 Dec.

Wapl is an essential regulator of chromatin structure and chromosome segregation.
Tedeschi A, Wutz G, Huet S, Jaritz M, Wuensche A, Schirghuber E, Davidson IF, Tang W, Cisneros DA, Bhaskara V, Nishiyama T, Vaziri A, Wutz A, Ellenberg J, Peters JM.
Nature. 2013 Sep.

The elongation complex components BRD4 and MLLT3/AF9 are transcriptional coactivators of nuclear retinoid receptors.
Flajollet S, Rachez C, Ploton M, Schulz C, Gallais R, Métivier R, Pawlak M, Leray A, Issulahi AA, Héliot L, Staels B, Salbert G, Lefebvre P.
PLoS One. 2013 Jun


A fractal model for nuclear organization current evidence and biological implications. 
Bancaud A., C. Lavelle, S. Huet and Ellenberg J. 
Nucleic Acids Res. 2012 Oct.

Dynamic hydroxymethylation of deoxyribonucleic acid marks differentiation-associated enhancers.
Sérandour AA, Avner S, Oger F, Bizot M, Percevault F, Lucchetti-Miganeh C, Palierne G, Gheeraert C, Barloy-Hubler F, Péron CL, Madigou T, Durand E, Froguel P, Staels B, Lefebvre P, Métivier R, Eeckhoute J, Salbert G
Nucleic Acids Res. 2012 Sep.

The novel antibacterial compound walrycin A induces human PXR transcriptional activity.
Berthier A, Oger F, Gheeraert C, Boulahtouf A, Le Guével R, Balaguer P, Staels B, Salbert G, Lefebvre P.
Toxicol Sci. 2012 May.

Myrip couples the capture of secretory granules by the actin-rich cell cortex and their attachment to the plasma membrane.
Huet, S.#, I. Fanget#, O. Jouannot, P. Meireles, T. Zeiske, N. Larochette, F. Darchen, Desnos C. 2012.
J Neurosci. 2012 Feb.


Tracking genomic hydroxymethylation by the base.
Salbert G, Weber M.
Nat Methods. 2011 Dec

Are 'omics of estrogen receptors defining potential targets for breast cancer treatment?
Métivier R.
Epigenomics. 2011 Oct

SORGOdb: Superoxide Reductase Gene Ontology curated DataBase.
Lucchetti-Miganeh C, Goudenège D, Thybert D, Salbert G, Barloy-Hubler F.
BMC Microbiol. 2011 May

Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers.
Sérandour AA, Avner S, Percevault F, Demay F, Bizot M, Lucchetti-Miganeh C, Barloy-Hubler F, Brown M, Lupien M, Métivier R, Salbert G*, Eeckhoute J*
Genome Res. 2011 Apr.


Biological and biophysical properties of the histone deacetylase inhibitor suberoylanilide hydroxamic acid are affected by the presence of short alkyl groups on the phenyl ring.
Oger F, Lecorgne A, Sala E, Nardese V, Demay F, Chevance S, Desravines DC, Aleksandrova N, Le Guével R, Lorenzi S, Beccari AR, Barath P, Hart DJ, Bondon A, Carettoni D, Simonneaux G, Salbert G.
J Med Chem. 2010 Mar


# co-first authors, * corresponding author(s), underlined team