SALBERT Group News

New Publication, Pinto Jurado E et al., Mol Biol Cell, Jan 2024

The recruitment of ACF1 and SMARCA5 to DNA lesions relies on ADP-ribosylation dependent chromatin unfolding.
Pinto Jurado E, Smith R*, Bigot N, Chapuis C, Timinszky G*, Huet S*.
Mol. Biol. Cell, Jan 2024.

PhD defence of Siham ZENTOUT

Etude de mécanismes régulant la dynamique de PARP1 aux niveaux des lésions de l'ADN.

New Publication, Longarini EJ et al., Mol Cell, May 2023.

Modular antibodies reveal DNA damage-induced mono-ADP-ribosylation as a second wave of PARP1 signaling.
Longarini EJ, Dauben H, Locatelli C, Wondisford AR, Smith R, Muench C, Kolvenbach A, Lynskey ML, Pope A, Bonfiglio JJ, Pinto Jurado E, Fajka-Boja R, Colby T, Schuller M, Ahel I, Timinszky G, O'Sullivan RJ, Huet S*, Matic I*.
Mol Cell, May 2023.

New Publication, Smith, Zentout et al., Nat Struct Mol Biol, Apr. 2023

HPF1-dependent histone ADP-ribosylation triggers chromatin relaxation to promote the recruitment of repair factors at sites of DNA damage
Smith R#*, Zentout S#, Rother M, Bigot N, Chapuis C, Mihuț A, Zobel FF, Ahel I, van Attikum H, Timinszky G*, Huet S*.
Nat Struct Mol Biol, Apr. 2023.

New Publication, d'Augustin et al., NAR, Apr 2023

Identification of key residues of the DNA glycosylase OGG1 controlling efficient DNA sampling and recruitment to oxidized bases in living cells.
D'Augustin O, Gaudon V, Siberchicot C, Smith R, Chapuis C, Depagne J, Veaute X, Busso D, Di Guilmi AM, Castaing B, Radicella JP, Campalans A*, Huet S*.
Nucleic Acid Res, Apr 2023.

Arrival of Christophe THIRIET

CNRS Researcher

PhD Defence of Ostiane d'AUGUSTIN

Mécanismes régulant la dynamique de l'ADN-glycosylase OGG1 en cellules vivantes.

New Publication, Laurent et al., Life Sci. Alliance, Mar. 2022

TET2-mediated epigenetic reprogramming of breast cancer cells impairs lysosome biogenesis
Laurent A, Madigou T, Bizot M, Turpin M, Palierne G, Mahé E, Guimard S, Métivier R, Avner S, Le Péron C*, Salbert G*
Life Sci. Alliance, Mar. 2022

New Publication, Lejart et al., Chromosoma, Mar. 2022

The N-terminal domain of TET1 promotes the formation of dense chromatin regions refractory to transcription.
Lejart A, Zentout S, Chapuis C, D'Augustin O, Smith R, Salbert G*, Huet S*.
Chromosoma, Mar 2022.

PhD Defence of Audrey LEJART

Caractérisation du rôle de la protéine Ten-Eleven Translocation 1 (TET1) dans la dynamique de l'organisation de la chromatine

Arrival of Gérard BENOÎT

Researcher INSERM

Arrival of Erwan WATRIN

Researcher CNRS

New Publication, Desapogu et al., Biomed Opt Express. 2021 Jul

Label-free microscopy of mitotic chromosomes using the polarization orthogonality breaking technique
Desapogu R, Le Marchand G, Smith R, Ray P, Gillier E, Dutertre S, Alouini M, Tramier M, Huet S*, Fade J*
Biomed Opt Express. 2021 Jul

New Publication, Juhasz et al., Science Advances, Dec. 2020

The chromatin remodeler ALC1 underlies resistance to PARP inhibitor treatment.
Juhász S*, Smith R*, Schauer T, Spekhardt D, Mamar H, Zentout S, Chapuis C, Huet S*, Timinszky G*
Science Advances 2020 Dec.

Arrival of Nicolas BIGOT

Post-Doc 2020-2022

Arrival of Marine JACQUIER

Assistant Professor