Rabut group

Our group is investigating ubiquitylation, a process that regulates the activity of thousands of proteins in our cells and that is linked to a broad range of diseases, from cancers to neurodegenerative disorders.


Selected publications

Sensitive detection of protein ubiquitylation using a protein-fragment complementation assay.
Le Boulch M, Brossard A, Le Dez G, Léon S, Rabut G.
J Cell Sci. 2020 May.

Protein quality control at the inner nuclear membrane.
Khmelinskii A#, Blaszczak E#, Pantazopoulou M, Fischer B, Omnus DJ, Le Dez G, Brossard A, Gunnarsson A, Barry JD, Meurer M, Kirrmaier D, Boone C, Huber W, Rabut G*, Ljungdahl PO*, Knop M*.
Corresponding authors - # Equal contribution
Nature. 2014 Dec.

CSN- and CAND1-dependent remodelling of the budding yeast SCF complex.
Zemla A, Thomas Y, Kedziora S, Knebel A, Wood NT, Rabut G, Kurz T.
Nat Commun. 2013 Mar.

The TFIIH subunit Tfb3 regulates cullin neddylation.
Rabut G*, Le Dez G, Verma R, Makhnevych T, Knebel A, Kurz T, Boone C, Deshaies RJ, Peter M*.
* Corresponding authors
Mol Cell. 2011 Aug.