Charlotte GUYOMAR

Equipe Microtubules, de la tubuline aux fuseaux

Email : charlotte [dot] guyomar [at] univ-rennes1 [dot] fr

Phone : +33 (0)2 23 23 65 63

MiToS team members

Address

Université de Rennes 1
UMR 6290, MiToS team
Campus de Beaulieu, Bât. 13, Pièce 204
35042 Rennes Cedex
France

In a few words

Charlotte Guyomar completed her Master's degree “Fundamental and Applied Microbiology” at the University of Rennes 1. She then continued as a PhD student at the IGDR in the “Ribosome Bacteria and Stress” team, under the supervision of Pr. Reynald Gillet (2015-2018). Then, Charlotte went on a 6-month post-doctoral fellowship at the University of Oxford (Sir William Dunn School of Pathology), under the supervision of Dr. Tanmay Bharat (2019). She is now a CNRS post-doctoral fellow in the "Microtubules, from Tubulin to Spindles" team.

Major publications

Changes in seam number and location induce holes within microtubules assembled from porcine brain tubulin and in Xenopus egg cytoplasmic extracts
Guyomar C, Bousquet C, Ku S, Heumann J, Guilloux G, Gaillard N, Heichette C, Duchesne L, Steinmetz M. O, Gibeaux R, Chrétien D
Elife 2022 Dec.

Insights into the ribosomal trans‐translation rescue system: lessons from recent structural studies
D’Urso G, Guyomar C, Chat S, Giudice E, Gillet R
The FEBS journal, 2022, Jan.

Structural heterogeneity of the microtubules lattice
Guyomar C, Ku S, Heumann J, Bousquet C, Guilloux G, Gaillard N, Heichette C, Duchesne L, Steinmetz M. O, Gibeaux R, Chrétien D
bioRxiv 2021.07.14.452321

Structures of tmRNA and SmpB as they transit through the ribosome
Guyomar C*, d'Urso G*, Chat S, Giudice E, Gillet R
Nat Commun, 2021 Aug
*Co-first authors

Determination of Microtubule Lattice Parameters from Cryo-electron Microscope Images Using TubuleJ
Ku S*, Messaoudi C*, Guyomar C, Kervrann C, Chrétien D
Bio-protocol 2020 Nov.
*Co-first authors

Reassembling green fluorescent protein for in vitro evaluation of trans-translation.
Guyomar C, Thépaut M, Nonin-Lecomte S, Méreau A, Goude R, Gillet R.
Nucleic Acids Res. 2020 Feb

Numerous cultivated and uncultivated viruses encode ribosomal proteins.
Mizuno CM, Guyomar C, Roux S, Lavigne R, Rodriguez-Valera F, Sullivan MB, Gillet R, Forterre P, Krupovic M.
Nat Commun. 2019 Feb

A Genetic Tool to Quantify trans-Translation Activity in Vivo.
Macé K, Demay F, Guyomar C, Georgeault S, Giudice E, Goude R, Trautwetter A, Ermel G, Blanco C, Gillet R.
J Mol Biol. 2017 Nov

Genomic and physiological analysis reveals versatile metabolic capacity of deep-sea Photobacterium phosphoreum ANT-2200.
Zhang SD, Santini CL, Zhang WJ, Barbe V, Mangenot S, Guyomar C, Garel M, Chen HT, Li XG, Yin QJ, Zhao Y, Armengaud J, Gaillard JC, Martini S, Pradel N, Vidaud C, Alberto F, Médigue C, Tamburini C, Wu LF.
Extremophiles. 2016 May

List of publications

Google Scholar

Patents

Guyomar C and Gillet R. Patent N° PCT/EP2018/063780. Reassembling GFP for study trans-translation activity and for novel antibiotic identification. (2018).

Awards

First prize of the Rennes 1 Foundation 2018 edition (Life Sciences research) for the structural study of trans-translation mechanism, a new target for the development of antibiotics.